THCV – Tetrahydrocannabivarin

Biochemistry: What is Tetrahydrocannabivarin (THCV)?

Originally THCV was most commonly isolated in landrace Sativa from the southern and central African continent. Until recently, Tetrahydrocannabivarin was not readily available due to the small concentrations present in Sativa strains. Strains have been developed to increase the yield of Tetrahydrocannabivarin. One, in particular, called Doug’s Varin has a ratio of 6:7 THC: THCV. This is the first strain that has been evaluated as containing more THCV than THC.

The Medical Benefits of THCV / Effects of Tetrahydrocannabivarin

  • Tetrahydrocannabivarin is more strongly psychoactive than THC. THCV however has about half the duration of THC.
  • THCV is considered a protagonist of THC, which means that it modifies the effects of THC. The energetic effect of THCV is more pronounced and stronger.
  • Tetrahydrocannabivarin has been discovered to reduce and in some instances even block panic attacks. It has been concluded that this result can may make THCV highly effective in the management of PTSD as well as other mental disorders where stress and anxiety initiate symptoms. This finding has been the result of studies in Israel where Medical Cannabis has been legal for some time. Tetrahydrocannabivarin doesn’t appear to suppress emotions, only suppressing the ability to panic, much of which is associated with Fight or Flight response.
  • Tetrahydrocannabivarin has been shown to reduce tremors that occur in  conditions such as Parkinson’s Disease along with ailments that effect motor control. There is research that also demonstrates THCV’s capability of reducing brain lesions associated with Parkinson’s.
  • Tetrahydrocannabivarin stimulates bone cell growth, and has great potential for treating osteoporosis and similar ailments.
  • THCV has a strong anorectic effect, which may cause concern as a side effect for patient’s already having difficulty eating.
  • Tetrahydrocannabivarinic Acid (THCV-A) is very similar to THC-A, and may prove to be an effective anti-inflammatory. Further testing is required.

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